A green miniaturized aqueous biphasic system prepared with cholinium chloride and a phosphate salt to extract and preconcentrate personal care products in wastewater samples

A miniaturized extraction/preconcentration method based on an aqueous biphasic system (μ-ABS) was developed with reagents commonly used as food additives: cholinium chloride (ChCl) main extraction phase, K2HPO4 salting-out agent, and water the component (being sample for analyses). With aim of obtaining high enrichment factors, miniaturization, adequate analytical performance, a point in region lowest amount ChCl selected, corresponding to 1.55% (w/w) ChCl, 59.5% K2HPO4, 38.95% water. The green μ-ABS (attending its elements performance mode) combination high-performance liquid chromatography diode-array detection (HPLC-DAD) determination 9 personal care products wastewater samples. μ-ABS-HPLC-DAD showed factors (up 100), quantitative efficiencies those compounds containing OH groups their structure, which can undergo hydrogen bonding ChCl. Thus, limits quantification down 0.8 µg·L-1 between 66.4 108% (concentration levels 1.3 13 µg·L-1) were reached group parabens UV-filter benzophenone-3. is characterized by use non-harmful absence organic solvents entire preparation procedure, while being simple, low-cost, easily compatible HPLC, highly efficient.